Structural formula
| Business number | 037H |
|---|---|
| Molecular formula | C5H7N3O4 |
| Molecular weight | 173.13 |
| label |
azoserine, o-Diazoacetyl-l-serine, aliphatic compounds |
Numbering system
CAS number:115-02-6
MDL number:MFCD00036802
EINECS number:204-061-6
RTECS number:None
BRN number:1726602
PubChem ID:None
Physical property data
1. Characteristics: light yellow to green Rhomboidal crystal. Maximum absorption wavelength 250.5nm (pH7, E1%/1cm 1140)252nm(0.1mol/L NaOH,E1%/1cm 1230).
2. Density (g/mL,25/4℃): Undetermined
3. Relative vapor density (g/mL,Air=1): Undetermined
4. Melting point (ºC): 146-162（ Decomposed)
5. Boiling point (ºC,normal pressure): Undetermined
6. Boiling point (ºC,5.2kPa): Not determined
7. Refractive index: Undetermined
8. Flashpoint (ºC): Undetermined
9. Specific optical rotation (º): [a]27.5/D-0.5° (c=8.46, in water, pH5.18).
10. Autoignition point or ignition temperature (ºC): Undetermined
11. Vapor pressure (kPa,25ºC): Undetermined
12. Saturated vapor pressure (kPa,60ºC): Undetermined
13. Heat of combustion (KJ/mol): Undetermined
14. Critical temperature (ºC): Undetermined
15. Critical pressure (KPa): Undetermined
16. Oil and water (octanol/Log value of the partition coefficient for water: undetermined
10. Autoignition point or ignition temperature (ºC): Undetermined
11. Vapor pressure (kPa,25ºC): Undetermined
12. Saturated vapor pressure (kPa,60ºC): Undetermined
13. Heat of combustion (KJ/mol): Undetermined
14. Critical temperature (ºC): Undetermined
15. Critical pressure (KPa): Undetermined
16. Oil and water (octanol/Log value of the partition coefficient for water: undetermined
17. Explosion limit (%,V/V): Undetermined
18. Lower explosion limit (%,V/V): Undetermined
19. Solubility: Very soluble Soluble in water, soluble in aqueous ethanol, slightly soluble in methanol, absolute ethanol and acetone. Aqueous solutions are most stable at pH8, and pH is higher or lower than 8 When , the stability decreases rapidly, and the neutral liquid can “℃”>100℃Heat 5 minutes. Incompatible with acids.
Toxicological data
None yet
Ecological data
None yet
Molecular structure data
None yet
Compute chemical data
1. Reference value for hydrophobic parameter calculation (XlogP): -2
2. Number of hydrogen bond donors: 2
3. Number of hydrogen bond acceptors: 6
p>
4. Number of rotatable chemical bonds: 4
5. Number of tautomers: none
6. Topological molecule polar surface area 124
7. Number of heavy atoms: 12
8. Surface charge: 0
9. Complexity: 240
10. Number of isotope atoms: 0
11. Determine the number of atomic stereocenters: 1
12. Uncertain number of atomic stereocenters: 0
13. Determine the number of chemical bond stereocenters: 1
14. Number of uncertain chemical bond stereocenters: 0
15. Number of covalent bond units: 1
Properties and stability
None yet
Storage method
Stored in a cool, ventilated warehouse. Keep away from fire and heat sources. They should be stored separately from oxidants, etc. and avoid mixed storage. Equipped with corresponding varieties and quantities of fire-fighting equipment. The storage area should be equipped with leakage emergency treatment equipment
Prepare and appropriate containment materials.
Synthesis method
Available by Diazoserine is extracted from the fermentation broth of actinomycetes and can also be synthesized by chemical methods.
Purpose
For transplantation of bacteria, molds, and animals and plants It has inhibitory effect on tumors. It is mainly used to treat acute leukemia and certain tumors and can be taken orally.
��; mso-bidi-font-family: 宋体; mso-font-kerning: 0pt”>17. Explosion Upper limit (%,V/V): Undetermined
18. Lower explosion limit (%,V/V): Undetermined
19. Solubility: Very soluble Soluble in water, soluble in aqueous ethanol, slightly soluble in methanol, absolute ethanol and acetone. Aqueous solutions are most stable at pH8, and pH is higher or lower than 8 When , the stability decreases rapidly, and the neutral liquid can “℃”>100℃Heat 5 minutes. Incompatible with acids.
Toxicological data
None yet
Ecological data
None yet
Molecular structure data
None yet
Compute chemical data
1. Reference value for hydrophobic parameter calculation (XlogP): -2
2. Number of hydrogen bond donors: 2
3. Number of hydrogen bond acceptors: 6
p>
4. Number of rotatable chemical bonds: 4
5. Number of tautomers: none
6. Topological molecule polar surface area 124
7. Number of heavy atoms: 12
8. Surface charge: 0
9. Complexity: 240
10. Number of isotope atoms: 0
11. Determine the number of atomic stereocenters: 1
12. Uncertain number of atomic stereocenters: 0
13. Determine the number of chemical bond stereocenters: 1
14. Number of uncertain chemical bond stereocenters: 0
15. Number of covalent bond units: 1
Properties and stability
None yet
Storage method
Stored in a cool, ventilated warehouse. Keep away from fire and heat sources. They should be stored separately from oxidants, etc. and avoid mixed storage. Equipped with corresponding varieties and quantities of fire-fighting equipment. The storage area should be equipped with leakage emergency treatment equipment
Prepare and appropriate containment materials.
Synthesis method
Available by Diazoserine is extracted from the fermentation broth of actinomycetes and can also be synthesized by chemical methods.
Purpose
For transplantation of bacteria, molds, and animals and plants It has inhibitory effect on tumors. It is mainly used to treat acute leukemia and certain tumors and can be taken orally.
微信扫一扫打赏
