sodium propionate

Structural formula

• Numbering system
• Physical property data
• Toxicological data
• Ecological data
• Molecular structure data
• Computing chemical data
• More
  • Properties and Stability
  • Storage method
  • Synthesis method
  • Purpose

Numbering system

CAS number:137-40-6

MDL number:MFCD00002759

EINECS number:205-290-4

RTECS number:UF7525000

BRN number:3566934

PubChem number:24898252

Physical property data

1. Properties: Colorless transparent granular crystals or white crystalline powder, easily deliquescent.

2. Solubility: soluble in water and ethanol.

3. pH value of aqueous solution: 8.5-10.5

Toxicological data

Acute toxicity data:

Rat route unknown LD50: 8150mg/kg

Mouse oral LC50: 6332mg/kg

Mouse route unknown LC50: 7800mg/kg

Rabbit skin LD50: 1640mg/kg

Rabbit route unknown LD50: 6750mg/kg

Other multiple dose data:

Rat route unknown TDLo: 24817mg/kg/9W-I is irritating

Ecological data

None

Molecular structure data

None

Compute chemical data

1. Reference value for hydrophobic parameter calculation (XlogP): None

2. Number of hydrogen bond donors: 0

3. Number of hydrogen bond acceptors: 2

4. Number of rotatable chemical bonds: 1

5. Number of tautomers: none

6. Topological molecule polar surface area 40.1

7. Number of heavy atoms: 6

8. Surface charge: 0

9. Complexity: 44.1

10. Number of isotope atoms: 0

11. Determine the number of atomic stereocenters: 0

12. Uncertain number of atomic stereocenters: 0

13. Determine the number of chemical bond stereocenters: 0

14. Number of uncertain chemical bond stereocenters: 0

15. Number of covalent bond units: 2

Properties and stability

Stable under normal temperature and pressure

Storage method

Sealed and dry storage

Synthesis method

1. Mainly adopt synthetic method. Propionic acid and sodium hydroxide are used as raw materials for synthesis reaction, and then dehydrated, refined and dried to obtain

2.Dissolve sodium carbonate in hot water, slowly add propionic acid at 70°C, then heat to boiling, control the ph value at 6.8~7.3, decolorize and filter , concentrate under reduced pressure, cool, filter and dry to get the finished product. The reaction formula is as follows:

3. Neutralized by propionic acid and sodium hydroxide, concentrated, crystallized, separated and dried And get.

4.Obtained from the neutralization of propionic acid and sodium hydroxide or sodium carbonate .

Purpose

1. Cosmetic preservatives. It has a wide range of antibacterial effects on molds, yeasts and bacteria. The antibacterial effect is particularly obvious in acidic solutes. The amount added in cosmetics is usually no more than 2%. Pesticides, fungicides. Determination of aminotransferases. It is used as a masking agent in tanning to improve the alkali resistance of the leather and the uniformity of tanning. 2.Sodium propionate is an acid-type food preservative, and its antibacterial effect is affected by the pH value of the environment. It has a strong inhibitory effect on various types of molds, Gram-negative bacilli or aerobic bacilli in acidic media. It is particularly effective in preventing the production of aflatoxin and is almost ineffective against yeast. In the food industry, it can be used to preserve pastries, and the usage amount is 2.5g/kg (calculated as propionic acid). 3.Sodium propionate is a preservative and has a strong inhibitory effect on various types of molds, aerobic bacilli or gram-negative bacilli in acidic media. . It is particularly effective in preventing the production of aflatoxin, but has almost no effect on yeast. It can also be used as a food preservative. 4.Used as a masking agent in tanning to improve the alkali resistance of the leather and the uniformity of tanning.