Structural formula
| Business number | 03YT |
|---|---|
| Molecular formula | C2HBrClF3 |
| Molecular weight | 197.38 |
| label |
Chlorotrifluoroethane, Halothane |
Numbering system
CAS number:151-67-7
MDL number:MFCD00009602
EINECS number:205-796-5
RTECS number:KH6550000
BRN number:1736947
PubChem number:24891772
Physical property data
1. Physical property data:
1. Characteristics: colorless Transparent and easy-flowing volatile liquid.
2 . Density (g/mL ,20/4℃):1.86
3 . Refractive index ( nD20）：1.3691
4 . Boiling point (ºC):50.2
5. Flash point (ºC): 49-50 ºC
6. Solubility: miscible with organic solvents and slightly soluble in water.
Toxicological data
2. Toxicological data:
1. Inhalation toxicity: Rat LC50: 29000ppm;
MouseLC50：98 mg/m3/2H
Ecological data
3. Ecological data:
Other harmful Effect: This substance may be harmful to the environment, and special attention should be paid to water bodies.
Molecular structure data
5. Molecular property data: 1. Molar refractive index:24.31 2. Molar volume (m3/ mol):102.8 3. Isotonic specific volume (90.2K): 223.3 4. Surface tension (dyne/cm3. Ecological data: Other harmful Effect: This substance may be harmful to the environment, and special attention should be paid to water bodies.
Molecular structure data
5. Molecular property data: 1. Molar refractive index:24.31 2. Molar volume (m3/ mol):102.8 3. Isotonic specific volume (90.2K): 223.3 4. Surface tension (dyne/cm): 22.1 5. Polarizability（10-24cm3):9.63
Compute chemical data
1. Reference value for hydrophobic parameter calculation (XlogP): None
2. Number of hydrogen bond donors: 0
3. Number of hydrogen bond acceptors: 3
4. Number of rotatable chemical bonds: 0
5. Number of tautomers: none
6. Topological molecule polar surface area 0
7. Number of heavy atoms: 7
8. Surface charge: 0
9. Complexity: 60.4
10. Number of isotope atoms: 0
11. Determine the number of atomic stereocenters: 0
12. Uncertain number of atomic stereocenters: 1
13. Determine the number of chemical bond stereocenters: 0
14. Number of uncertain chemical bond stereocenters: 0
15. Number of covalent bond units: 1
Properties and stability
Stable under normal temperature and pressure.
Incompatible materials:Strong oxidizing agentStorage method
Save in a dry and cool place.
Synthesis method
Produced from trifluorotrichloroethane through elimination, addition, rearrangement, reduction and other steps have to.
Purpose
This product is a commonly used new general inhalation anesthetic. The anesthetic effect is stronger and faster than ether, and the induction period is very short, but the analgesic and muscle relaxation effects are not strong, the dosage is small, and it is non-irritating. Can be used for minor surgeries or combined anesthesia. The disadvantage of this product is that it inhibits the heart and dilates blood vessels, which can lower blood pressure. The dilation of cerebral blood vessels leads to an increase in intracranial pressure and has an inhibitory effect on the respiratory center.
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5. Polarizability（10-24cm3):9.63
Compute chemical data
1. Reference value for hydrophobic parameter calculation (XlogP): None
2. Number of hydrogen bond donors: 0
3. Number of hydrogen bond acceptors: 3
4. Number of rotatable chemical bonds: 0
5. Number of tautomers: none
6. Topological molecule polar surface area 0
7. Number of heavy atoms: 7
8. Surface charge: 0
9. Complexity: 60.4
10. Number of isotope atoms: 0
11. Determine the number of atomic stereocenters: 0
12. Uncertain number of atomic stereocenters: 1
13. Determine the number of chemical bond stereocenters: 0
14. Number of uncertain chemical bond stereocenters: 0
15. Number of covalent bond units: 1
Properties and stability
Stable under normal temperature and pressure.
Incompatible materials:Strong oxidizing agentStorage method
Save in a dry and cool place.
Synthesis method
Produced from trifluorotrichloroethane through elimination, addition, rearrangement, reduction and other steps have to.
Purpose
This product is a commonly used new general inhalation anesthetic. The anesthetic effect is stronger and faster than ether, and the induction period is very short, but the analgesic and muscle relaxation effects are not strong, the dosage is small, and it is non-irritating. Can be used for minor surgeries or combined anesthesia. The disadvantage of this product is that it inhibits the heart and dilates blood vessels, which can lower blood pressure. The dilation of cerebral blood vessels leads to an increase in intracranial pressure and has an inhibitory effect on the respiratory center.
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