Toluene diisocyanate manufacturer Knowledge Application and preparation of nicotinamide anilide_Kain Industrial Additives

Application and preparation of nicotinamide anilide_Kain Industrial Additives

Background and overview[1][2]

Nicotinamide is an organic molluscicide, and 85% of nicotinamide is a gray powder solid. It is used to control blood snails and the effective concentration is 0.4-1.0 mg/L. Since nicotinamide is difficult to dissolve in water and affects the molluscicidal effect, it is generally made into nicotinamide sulfate or hydrochloride. Nicotinamide has a poor quick-acting effect on killing molluscs when used. It generally has a good effect only after 72 hours of use. The drug effect is long-lasting and has an impact on the environment and organisms.

Apply [1-2]

1. Used to prepare a compound pesticide preparation containing Spirocarb and nicotinamide

CN201510595048.6 provides a compound pesticide preparation containing Spirocarb and nicotinamide. The pesticide preparation has reasonable formula, low cost, easy use and good snail killing effect. The present invention adopts the following technical solution: a compound pesticide preparation containing Spirocarb and nicotinamide, which is composed of the following weight percentage raw materials:

The preparation method is:

A. Weigh Spirocarb, nicotinamide and auxiliaries according to a certain proportion;

B. Mix Luowei, nicotinamide and auxiliaries evenly to obtain a mixture;

C. Stir the mixture evenly and then crush it to 100-200 mesh. A compound pesticide preparation containing Spirocarb and nicotinamide was obtained.

How to use it:

A. According to the dosage of 3-5 grams per square meter, calculate the dosage according to the area to be used;

B. Weigh the agent and dissolve it in water, ensuring that the amount of water sprayed per square meter is not less than 1L;

C. Use a professional snail killer to spray the liquid evenly.

Compared with the existing technology, the beneficial effects and advantages of this invention are:

1. This pesticide preparation reduces the dosage of nicotinamide, reduces the pollution to cultivated land, soil and other environments, and reduces the toxic effect on environmental organisms.

2. This pesticide preparation improves the effect of killing oncomelania, which is better than using nicotinamide alone, and is less likely to produce drug resistance.

3. The usage amount of this pesticide preparation is lower than that of pesticide preparations containing Spirocarb or nicotinamide alone, and the cost is lower than that of nicotinamide pesticide preparations. Therefore, the usage cost of this pesticide preparation is low and the cost performance is high. .

2. Used in the preparation of molluscicides for aquaculture

CN200910273106.8 provides a synergistic snail-killing agent for aquaculture and its preparation method. The raw materials used in this method have wide sources, low cost, good water solubility, convenient processing, and the prepared snail-killing efficiency is high.

The technical solution provided by the invention is: a molluscicidal agent for aquaculture, including 5 to 80 wt% nicotinamide sulfate or nicotinamide hydrochloride, 1 to 30 wt% synergist, 9 to 30 wt% Copper sulfate or zinc sulfate and 10~45wt% diluent.

The preparation method of the above-mentioned molluscicide for aquaculture: the molluscicide for aquaculture contains 5 to 80 wt% nicotinamide sulfate or nicotinamide hydrochloride, 1 to 30 wt% synergist, 9 to 30 wt% The ratio of copper sulfate or zinc sulfate to 10 to 45wt% diluent is to crush nicotinamide sulfate or nicotinamide hydrochloride, synergist, copper sulfate or zinc sulfate and diluent respectively, and then mix and mix evenly. , to obtain a snail-killing agent for aquaculture. The grinding fineness of each of the above components is controlled between 10 and 100 mesh. The above-mentioned components can be mixed using the equal-increasing cross-mixing method: when the amount of diluent is greater than the amount of synergist, the steps for mixing and mixing uniformly are: (1) First, add a certain amount of synergist Mix with an equal amount of diluent to obtain Mixture 1, then add an equal amount of diluent to the aforementioned Mixture 1 and mix thoroughly, then increase the amount by multiples until all is mixed thoroughly to obtain Mixture 2; (2) Then add a certain amount of the main component sulfuric acid Mix nicotinamide and an equal amount of copper sulfate or zinc sulfate to obtain mixture 3, then add an equal amount of copper sulfate or zinc sulfate to the aforementioned mixture 3 and mix again, and increase the amount in this way until all is mixed to obtain mixture 4; (3 ) Add mixture 2 and mixture 4 obtained in step (2) directly into the mixer and mix evenly. When the amount of copper sulfate or zinc sulfate is greater than the amount of nicotinamide sulfate, the steps for mixing and mixing uniformly are: (1) first mix the synergist and diluent to obtain a mixture; (2) mix the main ingredients Mix nicotinamide sulfate and an equal amount of copper sulfate or zinc sulfate to obtain mixture 3, then add an equal amount of copper sulfate or zinc sulfate to the aforementioned mixture 3 and mix again, and increase the amount in this way until all is mixed to obtain mixture 4; ( 3) Add the mixture obtained in step (1) and mixture 4 directly into the mixer and mix evenly. When the amount of diluent is greater than the amount of synergist, and the amount of copper sulfate or zinc sulfate is greater than the amount of nicotinamide sulfate, the steps for mixing and mixing evenly are: (1) first mix the synergist with an equal amount Mix the diluent to obtain mixture 1, then add the same amount of diluent as the aforementioned mixture 1 and mix again, increase the amount in this way until all the mixture is mixed to obtain mixture 2; (2) Mix the main ingredient nicotinamide sulfate and an equal amount of Mix copper sulfate or zinc sulfate to obtain mixture 3, then add the same amount of copper sulfate or zinc sulfate as the aforementioned mixture 3 and mix again, increase the amount in this way until the mixture is completely mixed to obtain mixture 4; (3) Mix mixture 2 and mixture 4 Add directly to the mixer and stir to combine.

The raw materials used in the present invention have the characteristics of wide sources, low cost, good water solubility and convenient processing. Especially after using insecticide sheets, insecticide rings, badan, insecticides and other components, the snail killing efficiency has improved.It is further improved, the efficacy is stable, and the snails are killed faster and more thoroughly. When the water temperature is 22±1℃ and the concentration of the agent is 0.35ppm, 100% of the snails can be killed in 96 hours. Moreover, the product is low-toxic, safe for fish and shrimp, has no adverse effects on crops, aquatic plants, algae, and water for production and living of humans and livestock, and meets the requirements of ecological and environmental protection.

Main reference materials

[1] CN201510595048.6 A compound pesticide preparation and application containing spirarcarb and nicotinamide anilide

[2] CN200910273106.8 Molluscicidal agent for aquaculture and its preparation method

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