The importance of biological buffers has become increasingly prominent, and local companies will need to continue to improve their competitiveness in the future.

Biological buffer, also known as biological buffer, refers to a solution that can maintain a relatively stable pH value when adding a small amount of acid or alkali. Generally, it must be non-toxic, soluble in water but insoluble in organic solvents, non-absorbent to ultraviolet rays, and stable. It has the characteristics of good durability, strong buffering capacity, and is not disturbed by external factors such as temperature. Common biological buffer categories currently on the market mainly include phosphate buffer, Tris (tris (trishydroxymethylaminomethane)) buffer, HEPES (4-hydroxyethylpiperazineethanesulfonic acid) buffer, organic acid (acetate) , formate, citrate, succinate) buffer, etc. Among them, Tris buffer is the current mainstream product in the biological buffer market.

Biological buffers are most commonly used in the field of biochemistry. They mainly play a role in maintaining the normal pH value and normal physiological environment of organisms in biochemical research. They can also be used in the field of medical testing to maintain the normal blood pH range of the body. They can also be used for Molecular biology, coatings and other fields. In recent years, with the rapid development of the biochemical industry, the importance of biological buffers has become increasingly prominent, and the market has shown good development prospects. The domestic biological buffer market size will reach 2.17 billion yuan in 2022, a year-on-year increase of 16.2%.

Developed countries in Europe and the United States are at the forefront of the global biological buffer market by virtue of their early start and sufficient technical experience reserves. After years of development, a number of professional biological buffer manufacturers have been formed in their countries, such as Avantor in the United States, ANGUS in the United States, American Merck, American Bio-Rad, Swiss Lonza, etc. At present, the global and Chinese biological buffer markets are dominated by companies from developed countries in Europe and the United States.

According to the “Biological Buffer Industry Market In-depth Research and Investment Prospects Forecast Analysis Report 2023-2028” released by the Industrial Research Center, my country’s biological buffer industry started relatively late. The relevant production companies mainly include Tianjin Bailens Biotechnology, Shanghai Huicheng Biotechnology, Shanghai Cymbal Biotechnology, Shanghai Baisai Biotechnology, Shanghai Xibao Biotechnology, and Shandong Xingzhilian Biotechnology. Technology, Shenzhen Chengjiaxin Biotechnology, Hunan Wokai Biotechnology, Xi’an Aladdin Biotechnology, Suzhou Yake Technology, etc.

There are a large number of domestic biological buffer manufacturers. However, due to the rich subdivisions of biological buffers and the different technical difficulties of each product, most companies are generally small, scattered and weak. There is no obvious leading company. In the future, local leading companies will still need to be established. Continuously improve innovation capabilities and product quality, continue to expand product categories and enhance competitiveness.

Industry analysts said that biological buffers are used in biochemistry, molecular biology, medical testing and other fields. Important materials are needed. In recent years, with the rapid development of the domestic biomedical industry, its importance has become more and more prominent, and the industry has entered a critical period of rapid development. In the future, leading local biological buffer companies will need to continue to increase their innovation efforts and promote continuous improvement in competitiveness.