The sales volume of trimethylsilyl iodide (TMSI) in my country continues to grow, with the pharmaceutical field being its largest demand end.

Trimethylsilyl iodide (TMSI), also known as iodotrimethylsilane and iodotrimethylsilane, has a chemical formula of C3H9ISi and is a chemical substance. Trimethylsilyl iodide appears as a colorless or light red liquid and is soluble in most organic solvents. Trimethylsilane iodide has the characteristics of flammability and volatility. It is a common reagent in organic synthesis and has broad application prospects in the fields of medicine, pesticides and other fields.

There are two mainstream preparation methods for trimethyliodosilane: the first one uses excess hexamethyldisilane and iodine as raw materials, and directly prepares the finished product through a mixed reaction. This method has the advantages of less by-products and mild reaction, and is suitable for continuous chemical production; the second type uses hexamethyldisilane, iodine and aluminum powder as raw materials, reacts hexamethyldisilane and iodine, then adds aluminum powder, and obtains trimethyliodosilane through heating and distillation. In recent years, Chinese companies have continuously improved and optimized the preparation methods of trimethyliodosilane, driving the production of high-purity trimethyliodosilane to continue to increase.

As an organic iodide, trimethylsilyl iodide is widely used in medicine, pesticides and other fields. In the pharmaceutical field, trimethylsilyl iodide can be used as a pharmaceutical intermediate for the production of antiviral drugs, anticancer drugs, antibiotics, etc. The pharmaceutical field is the largest demand side for trimethylsilyl iodide, accounting for nearly 95% of the demand; in In the field of pesticides, trimethylsilane iodide can be used to produce insecticides, fungicides, herbicides, etc.

​ ​ Benefiting from the increasingly strong downstream demand, my country’s trimethyliodosilane industry has developed rapidly. According to the “2023-2028 China trimethylsilyl iodide (TMSI) industry market in-depth research and development prospect forecast report span>” shows that my country’s sales of trimethyliodosilane will reach 6.817 million tons in 2022, a year-on-year increase of 5.1%. Against the background of improving technological levels, my country’s sales of trimethylsilyl iodide will continue to grow in the future and are expected to reach 8.5 million tons by 2028.

my country’s trimethyliodosilane industry is highly concentrated, with leading companies occupying a larger market share. Shandong Boyuan Pharmaceutical Chemical Co., Ltd., Zhongshan Dixin Chemical Co., Ltd., Shandong Jiaying Chemical Technology Co., Ltd., Hubei Chengfeng Chemical Co., Ltd., Suzhou Qihang Biotechnology Co., Ltd., Yangzhou Sanyou Synthetic Chemical Co., Ltd., Quzhou Ruifeng Chemical Co., Ltd. and others are the main manufacturers of trimethylsilyl iodide in my country. The main products of Boyuan Co., Ltd. include precious metal catalysts, inorganic iodides and organic iodides, etc. Its organic iodide trimethyliodosilane accounts for nearly 70% of the Chinese market.

Industry analysts said that with the improvement of technical level, my country’s trimethyliodosilane industry is gradually developing in the direction of high quality. In recent years, my country’s enthusiasm for the research and development of antiviral and other drugs has been rising. As a pharmaceutical intermediate, trimethyliodosilane has seen an increasingly strong market demand. In terms of market competition, the trimethyliodosilane industry is highly concentrated, and Boyuan Co., Ltd. is the leading enterprise in my country.