Driven by the rapid development of the biopharmaceutical industry, the domestic substitution process in the domestic chromatography media market has accelerated.

Chromatography media is the core material of chromatography/chromatographic separation technology. Chromatographic separation technology, also known as chromatographic separation technology, refers to a method that uses the different physical and chemical properties of each component to separate and measure multi-component mixtures. Chromatography medium refers to the substances used to make up the chromatography system. It is a key material that affects the separation and purification effect of chromatographic separation technology and the analysis and detection performance.

There are many types of chromatography media. According to different separation mechanisms, chromatography media can be divided into affinity chromatography media, reversed-phase chromatography media, hydrophobic interaction chromatography media, ion exchange media, gel filtration media, etc.; according to different matrix materials , which can be divided into inorganic chromatography media and organic polymer chromatography media; according to different mobile phases, it can be divided into liquid chromatography media and gas chromatography media.

Chromatography/chromatography separation technology is mainly used in the field of biopharmaceuticals and is one of the key links in biopharmaceutical production. In this context, the main application scenarios of chromatography media have covered the separation and purification processes of the production of multiple types of drugs, such as vaccines, antibody drugs, recombinant protein drugs, cell and gene therapy drugs, and in vitro diagnostic APIs.

Currently, driven by the rapid development of the domestic biopharmaceutical industry, the market demand for chromatography media continues to increase. In 2022, the size of my country’s biopharmaceutical market will reach 451.87 billion yuan, a year-on-year increase of 12.1%. Therefore, according to the “2023-2028 Chromatography Media Industry Market In-depth Research and Investment Prospect Forecast Analysis Report” released by the Industrial Research Center It shows that the domestic chromatography media market size has reached 7.45 billion yuan in 2022, a year-on-year increase of 17.3%, and the industry has strong development momentum.

The particle size of chromatography media materials needs to be within the micron scale range, and the pore size needs to be within the range of 5-200 nanometers, and there are high requirements for morphology, structure, distribution, material composition, etc. The technical barriers to the industry are extremely high; layer There are various types of analysis media, and the downstream application fields of different products are quite different, resulting in more customization and supporting requirements in the downstream market, and high industry category barriers; downstream biopharmaceutical companies have a long product verification cycle, and generally they are not easily replaced after confirmation. Suppliers and chromatography media also have high customer barriers.

The chromatography media industry has high entry barriers. Foreign companies have first-mover advantages and sufficient reserves of technology and experience. They still occupy a dominant position in the global market. The leading international chromatography media companies mainly include GE of the United States, Cytiva of the United States, Bio-Rad of the United States, Agilent Technologies of the United States, Merck of Germany, Tosoh of Japan, etc.

Industry analysts said that my country’s chromatography media market is still dominated by leading international companies, and products are highly dependent on imports. But at the same time, driven by the continued favorable centralized procurement policies, the rapid development of the biopharmaceutical industry, and the gradual breakthroughs in key technologies by local companies, the domestic level of domestic chromatography media market is constantly improving. Domestic chromatography media companies mainly include NanoVis Technology, Borgron, Lanxiao Technology, Saifen Technology, etc. In the future, as the production capacity of local companies continues to be released, my country’s chromatography media market is expected to accelerate the realization of domestic substitution.