The application demand for piperazine and its derivatives is high and my country’s industrial structure needs to be adjusted

Piperazine, also known as p-diazine, is an organic compound with a colorless crystal appearance. Piperazine is soluble in water, glycerol, methanol, ethanol, etc., but insoluble in ether, benzene, etc., and the aqueous solution is alkaline. Piperazine is corrosive and hygroscopic. It can burn when exposed to open flames and decompose when exposed to high heat. As a fine chemical raw material, piperazine is widely used in the fields of medicine, electronics, chemicals, plastics, rubber and environmental protection, among which medicine is the main application scenario.

Piperazine is a six-membered heterocyclic ring containing two nitrogen atoms. Due to its structural characteristics, there are many piperazine derivatives, including anhydrous piperazine, hexahydrate piperazine, hexaoctapiperazine, and N,N’-dihydroxyethyl Piperazine, N,N’-diethylpiperazine, N-hydroxyethylpiperazine, etc. Among them, N-hydroxyethylpiperazine is the mainstream product in the market. With the advantages of low price and wide application, the N-hydroxyethylpiperazine market has grown rapidly in recent years.

According to the “2022-2026 China Piperazine and its Derivatives Industry Market Monitoring and Future Development Prospects Research Report》 shows that the application demand for piperazine and its derivatives is high. In 2021, the global market size of piperazine and its derivatives will reach about US$320 million. Globally, the market for piperazine and its derivatives is mainly distributed in North America, China, Europe and other regions. China is the largest consumer market for piperazine and its derivatives, accounting for more than 35.8%.

From a production perspective, suppliers of piperazine and its derivatives mainly include BASF of Germany, Dow of the United States, Nouryon, Sumitomo of Japan, Bayer of Germany, Shandong Alliance Chemicals, etc. In the past two years, due to the impact of the epidemic and international conflicts, there has been an energy shortage in Europe. Some manufacturers have closed piperazine-related production lines, resulting in insufficient supply of piperazine and its derivatives and a sharp rise in market prices. In 2021, the price of piperazine and its derivatives The increase reached more than 50.0%.

Foreign piperazine and its derivatives companies have high technical levels and mainly produce high-end products. In contrast, Chinese companies have a certain gap in technology, and the demand for high-end products still relies on imports. Take hexaoctapiperazine as an example. Hexaoctapiperazine is a high-performance derivative product. Due to high production technology requirements, the global and domestic markets are mainly occupied by foreign companies such as Nouryon, BASF, and Dow. Among them, Nouryon is The world’s largest hexaoctapiperazine production company has an annual production capacity of 12,000 tons. Shandong Alliance Chemical is the largest domestic hexaoctapiperazine production company, with an annual production capacity of only about 1,000 tons. There is a large gap with international leading companies. .

Industry analysts said that piperazine and its derivatives have many types, wide application fields and strong market demand. However, in the past two years, Affected by the epidemic and international conflicts, the supply of piperazine and its derivatives is insufficient, and the market price continues to increase. The production capacity of piperazine and its derivatives is relatively concentrated. Due to the low technical level of domestic enterprises, domestic piperazine and its derivatives are mostly concentrated in the mid-to-low-end fields. With consumption upgrading, the industrial structure of piperazine and its derivatives in my country still needs to be adjusted.