Tolbutamide Tolbutamide

Structural formula

• Numbering system
• Physical property data
• Toxicological data
• Ecological data
• Molecular structure data
• Computing chemical data
• More
  • Properties and Stability
  • Storage method
  • Synthesis method
  • Purpose

Numbering system

CAS number:64-77-7

MDL number:MFCD00027169

EINECS number:200-594-3

RTECS number:YS4550000

BRN number:1984428

PubChem number:24277742

Physical property data

1. Character:White crystalline powder. Odorless and tasteless

2. Density (g/mL,25/4℃): Unsure

3. Relative vapor density (g/mL,AIR=1): Unsure

4. Melting point (ºC):128 -130

5. Boiling point (ºC,Normal pressure): Uncertain

6. Boiling point (ºC, 5.2kPa): Unsure

7. Refractive index:Not sure

8. Flash point (ºC): Unsure

9. Specific optical rotation (º): Unsure

10. Autoignition point or ignition temperature (ºC): Unsure

11. Vapor pressure (kPa,25ºC): Unsure

12. <SPAN style="FONT-SIZE: 9pt; FONT-FAMILY: 宋体; mso-ascii-font-family: Arial; mso-hansi-font-fa): 583.5

4. Surface Tension (dyne/cm):42.7

5. Polarizability（10^-24cm³): 28.05

Compute chemical data

1. Reference value for hydrophobic parameter calculation (XlogP): None

2. Number of hydrogen bond donors: 2

3. Number of hydrogen bond acceptors: 3

4. Number of rotatable chemical bonds: 5

5. Number of tautomers: 3

6. Topological molecule polar surface area 83.6

7. Number of heavy atoms: 18

8. Surface charge: 0

9. Complexity: 354

10. Number of isotope atoms: 0

11. Determine the number of atomic stereocenters: 0

12. Uncertain number of atomic stereocenters: 0

13. Determine the number of chemical bond stereocenters: 0

14. Number of uncertain chemical bond stereocenters: 0

15. Number of covalent bond units: 1

Properties and stability

None yet

Storage method

This product should be sealed in 0℃Save the following in a dry place and away from light.

Synthesis method

Prepared from the condensation of butyl isocyanate and p-toluenesulfonamide, or from the condensation of n-butylamine hydrochloride and toluenesulfonylurea become.

Purpose

A hypoglycemic drug, suitable for adult patients with stable mild to moderate diabetes.

ng=EN-US style=”FONT-SIZE: 9pt; FONT-FAMILY: Arial; mso-font-kerning: 0pt”>

Purpose

A hypoglycemic drug, suitable for adult patients with stable mild to moderate diabetes.