D(-)-Salicin

Structural formula

• Numbering system
• Physical property data
• Toxicological data
• Ecological data
• Molecular structure data
• Computing chemical data
• More
  • Properties and Stability
  • Storage method
  • Synthesis method
  • Purpose

Numbering system

CAS number:138-52-3

MDL number:MFCD00006590

EINECS number:205-331-6

RTECS number:LZ5901700

BRN number:89593

PubChem number:24899442

Physical property data

Properties: colorless crystal or white powder. Hygroscopic.
Relative density: 1.434
Melting point: 199~202
Solubility: Soluble in water, boiling water, ethanol, pyridine, alkali and glacial acetic acid, almost insoluble in ether and chloroform.

Toxicological data

Acute toxicity data :

Mouse abdominal cavity LD：>500mg/kg

Ecological data

None

Molecular structure data

Molecular property data:

1, Molar refractive index：68.41

2, Molar volume（m³/mol):190.3

3, Isotonic specific volume（90.2K）：550.7

4, Surface tension（3.0 dyne/ cm):70.1

5, Polarizability（0.5 10 ^-24cm³):27.12

Compute chemical data

1. Reference value for hydrophobic parameter calculation (XlogP): None

2. Number of hydrogen bond donors: 5

3. Number of hydrogen bond acceptors: 7

4. Number of rotatable chemical bonds: 4

5. Number of tautomers: none

6. Topological molecule polar surface area 120

7. Number of heavy atoms: 20

8. Surface charge: 0

9. Complexity: 300

10. Number of isotope atoms: 0

11. Determine the number of atomic stereocenters: 5

12. Uncertain number of atomic stereocenters: 0

13. Determine the number of chemical bond stereocenters: 0

14. Number of uncertain chemical bond stereocenters: 0

15. Number of covalent bond units: 1

Properties and stability

None

Storage method

Store sealed and dry.

Synthesis method

None

Purpose

Naturally found in Salicaceae plant Salix(Salix babylonica L.)in branches, stems and other plants. It can be obtained through chemical synthesis. After oral administration15~30min, salicinogen, salicylic acid, etc. can appear in urine, therefore, it has Antipyretic, analgesic, anti-inflammatory, anti-rheumatic and other effects. Because this transformation is not constant, its therapeutic value is lower than that of salicylic acid. In addition, it also has a bitter taste, stomachic and local anesthetic effects. It can also be used as a biochemical reagent.
Substrate for determination of b-glycosidase .

AN style=”FONT-SIZE: 9pt; FONT-FAMILY: Arial; mso-font-kerning: 0pt; mso-fareast-font-family: Arial”>（0.5 10^-24cm³):27.12

Compute chemical data

1. Reference value for hydrophobic parameter calculation (XlogP): None

2. Number of hydrogen bond donors: 5

3. Number of hydrogen bond acceptors: 7

4. Number of rotatable chemical bonds: 4

5. Number of tautomers: none

6. Topological molecule polar surface area 120

7. Number of heavy atoms: 20

8. Surface charge: 0

9. Complexity: 300

10. Number of isotope atoms: 0

11. Determine the number of atomic stereocenters: 5

12. Uncertain number of atomic stereocenters: 0

13. Determine the number of chemical bond stereocenters: 0

14. Number of uncertain chemical bond stereocenters: 0

15. Number of covalent bond units: 1

Properties and stability

None

Storage method

Store sealed and dry.

Synthesis method

None

Purpose

Naturally found in Salicaceae plant Salix(Salix babylonica L.)in branches, stems and other plants. It can be obtained through chemical synthesis. After oral administration15~30min, salicinogen, salicylic acid, etc. can appear in urine, therefore, it has Antipyretic, analgesic, anti-inflammatory, anti-rheumatic and other effects. Because this transformation is not constant, its therapeutic value is lower than that of salicylic acid. In addition, it also has a bitter taste, stomachic and local anesthetic effects. It can also be used as a biochemical reagent.
Substrate for determination of b-glycosidase .