3-Chloro-2-methylaniline

Structural formula

• Numbering system
• Physical property data
• Toxicological data
• Ecological data
• Molecular structure data
• Computing chemical data
• More
  • Properties and Stability
  • Storage method
  • Synthesis method
  • Purpose

Numbering system

CAS number:87-60-5

MDL number:MFCD00007766

EINECS number:201-756-6

RTECS number:XU4760000

BRN number:471697

PubChem number:24846547

Physical property data

1. Character: liquid, can be Water vapor evaporates and quickly turns brown in the air

2. Density (g/mL,25/4℃): 1.171

3. Relative vapor density (g/mL,air =1): Undetermined

4. Melting point (ºC): 2℃

5. Boiling point (ºC,Normal pressure): 245℃ (ºC,0.67kpa or 5 mmHg)

6. Boiling point (ºC,5.2kPa): 115-117℃ (ºC,1.33kpa)

7. Refractive index: 1.588-1.59

8. Flashpoint (ºC): 112.8℃

9. Specific optical rotation (º) : Undetermined

10. Autoignition point or ignition temperature (ºC): Undetermined

11. Vapor pressure (kPa,25ºC): Undetermined

12. Saturation vapor pressure (kPa,60ºC): Undetermined

13. Burning heat (KJ/mol): Undetermined

14. Critical temperature (ºC): Undetermined

15. Critical pressure (KPa): Undetermined

16. Oil and water (octanol/Log value of the partition coefficient for water: undetermined

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8. Surface charge: 0

9. Complexity: 94.9

10. Number of isotope atoms: 0

11. Determine the number of atomic stereocenters: 0

12. Uncertain number of atomic stereocenters: 0

13. Determine the number of chemical bond stereocenters: 0

14. Number of uncertain chemical bond stereocenters: 0

15. Number of covalent bond units: 1

Properties and stability

None yet

Storage method

This product is sealed and stored in a cool, dry place.

Synthesis method

By O-nitrotoluene is obtained by chlorination and reduction. 1.Chlorinated in o-nitrotoluene , add 2% Iron acts as a catalyst in50-60℃ Pour in chlorine until the relative density of the reaction solution reaches1.27-1.29（50℃) Until now, use 5% Hydrochloric acid washing, and then Wash with water, and finally adjust the pH with liquid alkalipH for7. Separate the water layer, evaporate the water, and conduct vacuum distillation to collect120-150℃（) fraction, cool, crystallize and filter to obtain2-chlorine-6-Nitrotoluene. 2.Reduction Add hydrochloric acid and iron powder Stir and heat in the reaction pot until 90℃ , slowly add the melted2-Chlorine -6-Nitrotoluene, added , reflux reaction3h. Cool, add liquid alkali to adjustpH is8, steam distilled, get 3-Chloro-o-toluidine.

Purpose

Organic synthesis intermediates.

Add acid and iron powder to the reaction pot, stir and heat until 90℃, slowly add the melted2-Chlorine-6 –Nitrotoluene, addition completed, reflux reaction3h. Cool, add liquid alkali to adjustpH is8, steam distilled, get 3-Chloro-o-toluidine.

Purpose

Organic synthesis intermediates.