Preparation method of (4S)-3-[(5S)-5-(4-fluorophenyl)-5-hydroxypentanoyl]-4-phenyl-1

Background and overview[1] Ezetimibe was jointly developed by Schering-Plough and Merck for the treatment of hyperlipidemia. It was approved by the U.S. FDA in 2002 under the trade name Zetia. Its che…