Preparation of Sitagliptin Impurity 13_Kain Industrial Additive

Background and overview[1] Sitagliptin, chemical name (2R)-4-oxo-4-[3-trifluoromethyl-5,6-dihydro[1,2,4]triazole[4 , 3-a]pyrazin-7(8H)-yl]-1-(2,4,5-trifluorophenyl)-butan-2-amine, which is a dipeptide…

Preparation of Sitagliptin Impurity 13_Kain Industrial Additive

Background and overview[1] Sitagliptin, chemical name (2R)-4-oxo-4-[3-trifluoromethyl-5,6-dihydro[1,2,4]triazole[4 , 3-a]pyrazin-7(8H)-yl]-1-(2,4,5-trifluorophenyl)-butan-2-amine, which is a dipeptide…

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